![]() ![]() There is sclerosis of the larger vessels, with their lumen being filled with extracellular glial tissue, giving lattice degeneration its characteristic fibrotic appearance. It appears to be due to dropout of peripheral retinal capillaries with resulting ischemia, which induces thinning of all retinal layers. Lattice degeneration is typically bilateral. A tractional linear tear will occur on the posterior edge of lattice lesions in 1.9 percent of lesions. The incidence of atrophic holes in lattice degeneration ranges from 18 to 42 percent. ![]() Atrophic holes are often present in the lesion, occasionally large enough to encompass the entire lattice lesion. There may be associated RPE hyperplasia, giving the lesion a pigmented appearance. The individual lesions are usually from one-half to six disc diameters and may run 360 degrees around the eye in a discontinuous pattern. It nearly always runs circumferentially between the equator and the ora serrata. It presents as a linear trail of fibrosed vessels within atrophied retina in a "lattice" pattern. Lattice degeneration occurs in eight to 11 percent of the general population. There is no racial or sexual predilection. There appears to be a higher incidence of myopia in patients with lattice degeneration. The patient is usually over age 20 and is nearly always asymptomatic, except for possible complaints of flashing lights (photopsia). ![]()
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